Sildenafil (Viagra) and its effects on fertility in women and men

Sildenafil, commonly known as Viagra, is a medication primarily used to treat erectile dysfunction in men. However, its impacts extend beyond its primary use. There is no clear evidence to suggest that taking sildenafil reduces fertility in either women or men. An in vitro study found no effects on sperm motility at concentrations approximately 4000 times peak semen concentration following the highest recommended therapeutic dose (100 mg) of sildenafil. In fact, sildenafil-based drugs like Viagra can have a positive effect on fertility by increasing the frequency of sexual encounters.

Sildenafil use and pulmonary hypertension

Sildenafil has also been used in the treatment of pulmonary hypertension, a condition characterized by high blood pressure in the arteries of the lungs. It's important to note that if you have pulmonary hypertension and are trying for a baby, you should use reliable contraception and consult your doctor.

The importance of reliable contraception during sildenafil use

While sildenafil is generally safe for use in men and women, it's crucial to consult a healthcare professional if you're planning to conceive. The advice of a doctor is necessary to understand the potential risks and benefits associated with sildenafil use during this period.

Risks and precautions of sildenafil use during pregnancy

Pregnant women considering sildenafil use should be aware of certain risks.

Studies of small numbers of pregnant women taking sildenafil do not currently suggest that this can cause preterm birth or low infant birth weight.However, a few cases have reported a rare complication called persistent pulmonary hypertension of the newborn (PPHN) in babies born to women who took sildenafil during pregnancy.

Sildenafil and fetal growth restriction

Contrarily, sildenafil has shown potential in improving fetal growth under suboptimal intrauterine conditions. A meta-analysis supports that sildenafil improves fetal growth and maternal blood pressure regulation during fetal growth restriction (FGR) and preeclampsia pregnancy. However, this significant improvement is not observed in healthy pregnant groups.

Sildenafil as a potential therapy for selected maternal and fetal disorders

Despite the reduced number of pregnant women taking sildenafil even for maternal cardiac indications, there is no report of teratogenicity. There is growing evidence that it may be used in select situations during pregnancy. This includes when the mother has severe pre-eclampsia, and in fetuses whose growth has been restricted.

The importance of doctor consultation before using sildenafil during pregnancy

Given the varying effects of sildenafil during pregnancy, it is absolutely essential to consult with a healthcare professional before its use. Doctors can provide guidance on the potential risks and benefits, ensuring that sildenafil use is tailored to individual circumstances, prioritizing the safety and health of both mother and baby.

To conclude, while sildenafil has been shown to have potential benefits during pregnancy, its use should be carefully considered and monitored by a healthcare professional. It's necessary to balance the potential risks with the benefits, ensuring the wellbeing of both the mother and the unborn child.